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Image Featured on the Cover of Biology Open

An image acquired using the Leica TCS SP8 Confocal Microscope with White Light Laser (WLL) at our microscopy facility was featured on the cover of Biology Open, as part of the publication 'Nucleolar stress in Drosophila neuroblasts, a model for human ribosomopathies' by Sonu S. Baral, a former doctoral student in Dr. Patrick J. DiMario’s laboratory.

Sonu S. Baral

Patrick J. DiMario

 

Biology Open Cover Volume 9 (4) April 2020

In a study by Baral and colleagues wild-type (w1118) larval brains at 3 days old were EdU pulse labelled (Click-iT Alexa Fluor 594) for 30 min to visualize all S-phase cells: neuroblasts (NB) and ganglionic mother cells (GMCs). This merged confocal image shows EdU-labelled cells (magenta; mushroom body NBs and their GMCs) nestled within the GFP-labelled mushroom body NBs lineage (green) near the posterior regions of the central brain lobe. Scale bar: 50 microns. Image licensed under a Creative Commons Attribution 4.0 International license.